Analytical Study of Multi Stages Breast Cancer Mathematical Model Using Fractional Calculus

Authors

  • Eiman Eiman University of Malakand
  • Kamal Shah Department of Mathematics University of Malakand
  • Thabet Abdeljawad Prince Sultan University
  • Hussam Alrabaiah Al Ain University

DOI:

https://doi.org/10.29020/nybg.ejpam.v19i2.7288

Keywords:

Epidemiological model; Multi stage breast cancer; Cardiotoxicity; CFFD; Laplace transform.

Abstract

In this manuscript, we investigate a mathematical model for breast cancer with chemotherapy treatment. Considered model is a six compartmental mathematical model for breast cancer having four stages of breast cancer, recovery and cardiotoxicity. Nonlocal fractional order derivative due to Caputo-Fabrizio is used for the considered study. The mentioned derivative has the ability to avoid singularity due to its nonlocal and nonsingular kernel. The considered model is investigated for qualitative analysis and also approximate solutions. Analysis is made on the basis of analytical method. Since breast reast cancer, is one of the most spreading cancer in the world which starts in the breast tissue. Type of breast cancer and overall health determine how it can be treated. Radiation, hormone therapy, chemotherapy, and surgery are among the available treatments. Usually, chemotherapy is used to treat it. Most chemotherapy drugs are quite effective at preventing cancer from spreading throughout the body. Chemotherapy, however, can result in cardiotoxicity due to its effects on blood arteries and heart muscle. A graphical presentation corresponding to some fundamental data is given via using MATLAB 2023.

Author Biographies

  • Eiman Eiman, University of Malakand

    Lecturer in University of Malakand

  • Kamal Shah, Department of Mathematics University of Malakand

    University of Malakand/Prince Sultan University

  • Thabet Abdeljawad, Prince Sultan University

    Professor in Prince Sultan University

  • Hussam Alrabaiah, Al Ain University

    Professor in AL Ain university

References

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Published

2026-07-28

Issue

Section

Mathematical Biosciences

How to Cite

Analytical Study of Multi Stages Breast Cancer Mathematical Model Using Fractional Calculus. (2026). European Journal of Pure and Applied Mathematics, 19(2), 7288. https://doi.org/10.29020/nybg.ejpam.v19i2.7288